A team led by famed Harvard Medical School anti-aging researcher David Sinclair has just published a paper that shows a mix of chemicals are capable of reversing cellular aging...
A hallmark of eukaryotic aging is a loss of epigenetic information, a process that can be reversed. We have previously shown that the ectopic induction of the Yamanaka factors OCT4, SOX2, and KLF4 (OSK) in mammals can restore youthful DNA methylation patterns, transcript profiles, and tissue function, without erasing cellular identity, a process that requires active DNA demethylation. To screen for molecules that reverse cellular aging and rejuvenate human cells without altering the genome, we developed high-throughput cell-based assays that distinguish young from old and senescent cells, including transcription-based aging clocks and a real-time nucleocytoplasmic compartmentalization (NCC) assay. We identify six chemical cocktails, which, in less than a week and without compromising cellular identity, restore a youthful genome-wide transcript profile and reverse transcriptomic age. Thus, rejuvenation by age reversal can be achieved, not only by genetic, but also chemical means.
Is this how most people type on mobile these days, drawing lines all over a keyboard instead of tapping the individual keys? I've never had an iPhone so I don't even know if they can do this natively, but I know you can switch keyboards at least, so it should still be an option if not.
::: spoiler Logline La’An travels back in time to twenty-first-century Earth to prevent an attack which will alter humanity’s future history—and bring her face to face with her own contentious legacy. :::...
Seen hiking along the Quilcene River (startrek.website)
What thematic instances are there, and what others do you wish there were?
Instances where most communities are related to a main subject, like programming.dev
Harvard Scientist Says He's Found a Cocktail That Can Reverse Aging in Human Cells (www.sciencealert.com)
A team led by famed Harvard Medical School anti-aging researcher David Sinclair has just published a paper that shows a mix of chemicals are capable of reversing cellular aging...
GOP lawmakers predict ‘fistfight’ between Marjorie Taylor Greene and Lauren Boebert (www.independent.co.uk)
Tension between the two congresswomen has been rising in recent weeks
Do you have a favorite film scene that you come back to again and again? (kbin.social)
For me, it has to be this, the final scene from Stanley Kubrick's "Paths Of Glory".
What movie did you rewatch most often?
For me, it’s either the Matrix or Pulp Fiction. I have seen both a lot of times but certainly not more often than say a dozen times.
Do you use the swipe to type feature on your phone? (kbin.social)
Is this how most people type on mobile these days, drawing lines all over a keyboard instead of tapping the individual keys? I've never had an iPhone so I don't even know if they can do this natively, but I know you can switch keyboards at least, so it should still be an option if not.
Lawyers with supreme court business paid Clarence Thomas aide via Venmo (www.theguardian.com)
Payments to Rajan Vasisht, an aide from 2019-21, underscore ties between the justice and lawyers who argue cases in front of him
Forgotten Beasts with fire, smoke and webs
Any idea how to face and defeat this monstrosity?
What are your Lemmy/Fediverse tips and tricks for those who are just joining or thinking of joining?
Could be anything associated with the Fediverse, Lemmy, Mastodon, Pixelfed etc.
Jim is invading the "finer things club", aka kbin.social is only our launchpad for the fediverse. We should think about finding another instance soon. (kbin.social)
For the last few weeks we enjoyed a much better content on kbin than we had on reddit for a long time....
Episode Discussion | Star Trek: Strange New Worlds | 2x03 "Tomorrow and Tomorrow and Tomorrow"
::: spoiler Logline La’An travels back in time to twenty-first-century Earth to prevent an attack which will alter humanity’s future history—and bring her face to face with her own contentious legacy. :::...
So how does lemmy make money?
I'm not seeing any ads, and these servers certainly have a cost.... So is this place entirely donation based, or what?
UPDATED 9-3: StarTrek.website - Lemmy info, FAQ, Patreon info, future plans, and more!
https://startrek.website/pictrs/image/590456a7-0f95-4e61-968a-c688dd564033.jpeg...
lemmur can't find startrek.website (startrek.website)
I get “instance not found”