I’m not sure why people think reptiles are slimy, they’re not, their skin feels more leathery or like smooth plastic or vinyl. Hardly what I would call slimy. Amphibians are slimy, which makes sense since amphibians have permeable skin but reptiles have impermeable skin (it’s actually more impermeable than ours) so it stands to reason that to would not feel wet or slimy at all, and they pretty much don’t.
I would disagree though that pythons feel smooth, they do still have that rough reptilian feel, they don’t don’t feel gross though, at least I don’t think so. If you have Herpetophobia you might disagree with my take.