I had a sinus infection for several years. Doctors threw every antibiotic at me and nothing stuck. Was told to take antihistamines and see if it cleared up.
I ended up with a bunch of dental cavities from dry mouth and said Enough - I got an appointment with another doctor and pleaded with them for a different prescription. Antifungal. A week later it was gone.
I'm fascinated at how much more we (at least the public) are discovering of the effects of climate change. Basic level was: hotter years, and then we discover new mechanics that comes with this change
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