Are you advocating for some form of isolation? If so, what?
Kernel sandboxing. I mean, breaking out of browser “sandboxes” is a game these days.
Any site you browse to – including those not labeled as such – could well expose you to that vulnerability.
Which is why using the web without JavaScript is a security measurement which I strongly recommend to enable. Sure, many sites will be “less interactive” then, but I’m afraid that it is the only solution. For the usually: rather small number of websites which you absolutely need to use with JavaScript enabled (do you, really?), a separate browser inside a container (or VM) would be a good option. I admit that this is not the most comfortable setup, but I really prefer to be safe than sorry. YMMV, but you asked.