I’ve been daily driving a Debian 11 Proxmox VM running on an HP ProDesk Elite SFF with an i7-6700T and an ancient Nvidia GeForce GT 730 passed through.
I access it via ThinLinc running on a Dell Wyse 5070 Extended thin client. Works really well, even video isn’t bad, but it’s not for gaming.
For gaming, I’m working on setting up a Nobara VM with an Nvidia Tesla P4 passed through.