I don’t know if you’re asking because of my recent post on [email protected], but if you’re worried that someone might put a virus or some kind of remote hack into your device, you have nothing to worry about or shouldn’t, as I said in a response to the post, unless you are connected to dubious or public WiFi where anyone can run adb, no one can do anything to you and I say this because at least on my device, my device only activates debugger mode if it is connected specifically to a network that I, the user, identify as safe, otherwise it cannot be activated.
Short Answer: No, you have nothing to worry about, just don’t tell your phone that any public network is trusty unless you’re connected to a VPN.