Disney would be in-fucking-sane to let go of an MCU Spidey. It would be like having X-men without Professor X, or removing some other staple hero. Spidey is far and away one of the most valuable singular heroes in the Marvel Universe, alongside Iron Man, Cap, and perhaps Wolverine, and each of those only truly became MASSIVELY popular after the movies. Spidey was already a juggernaut before that, in the comics world, and the Maguire movies.
No way do we not get another MCU spidey, whether it’s Holland or not.