I guess potentially they will be able to make a Cyberpunk 2077 sequel on Unreal Engine maybe called Cyberpunk 2078: Edgerunner Boogaloo (CDPR I am available to join your team, get in touch).
I know precisely the square root of fuck all when it comes to game design but presuming they can at least map across assets as they will already have the character designs, language, city design etc all sorted so hopefully they will be starting from a lot further forward than CB2077 years ago.