Maybe not exactly what you were getting at but the start of Prey (2017) really stands out to me. I don’t want to ruin it for anyone who hasn’t played it, but it’s was one of the few times a game actually made me pause to seriously reflect the situation.
If you do get the game don’t look at any reviews or guides if you get stuck before you reach the Talos 1 Lobby.
Massive spoiler for the first hour of the game, seriously don’t read unless you don’t play games:
spoilerYou take a helicopter ride from an apartment to take some tests before you are to go to a space station. Only one of the testers is attacked by something alien and you are knocked out by a test chamber’s gas. You wake up on the same day back in your apartment, but this time there’s a dead person in the hall way and you’re stuck in the apartment building. Breaking the window of your apartment (something you aren’t prompted to even do) reveals the entire space you traveled the prior day has been theater conducted inside a massive testing chamber already on the space station you were told you were heading to.