uBlock does a nice job of blocking well known advertisements.
However NoScript, is more secure because it disables all JS by default.
While offering you an easy UI to (temporarily/permanently) whitelist individual components.
Keep in mind, this will cause rather heavy site breakage in the first few weeks of using it.
However that will get better once you whitelisted the bare essentials for the sites you regularly visit.
Most sites use 0 to 3 JS sources enabled in NoScript to read/work correctly.
While spy-ware/telemetry infested sites will ship with up to 15 or so JS sources.