Yes, with the caveat that the combination of weather and local adaptations is more important than weather alone. For example, the heat is worse in Florida than it is in New York City, but in Florida you can drive everywhere in an air-conditioned car and experience the heat for only a minute or two each day while in NYC you’ll probably have to either walk or wait for mass transit long enough to become miserable even though the weather isn’t as hot.
It seems that unless you can live somewhere with perfect weather like parts of the west coast of the US, you’re probably best off looking for the most car-friendly place to live and avoiding the weather entirely.