Microbes in my mouth that produce ethanol instead of acid? You are all wrong here, this is ideal. I'm sure it's 100% safe to have https://en.wikipedia.org/wiki/Auto-brewery_syndrome but only in your mouth. Make sure to wash your mouth out with everclear whenever you brush, just to be safe.
Watch me bring them something unnecessarily overcomplicated that boosts their ego to win all of the money.
A micropayment platform designed to integrate with long form textual content. The subscribers will be able to vote with their wallets on the topic they wish the CONTENT_CREATOR to cover.
But there’s a game theoretic twist. The final price of each vote will be discounted based on the share of votes it received, so if you vote for the winning option, your votes will end up costing less. This encourages strategic voting based on what would be the most interesting topic to the largest share of subscribers, incentivizing subscribers to maximize for total utility instead of just their own interests.
Additionally, below a certain threshold of share the votes will be free of charge. This is to encourage heterodox views and foster engagement with unconventional interests that would otherwise be risky to vote for.
The cutoff for the free Complimentary Contrarian’s Votes will be determined by a prediction market running in parallel with the vote.
The winning votes will become investments into the post, binding the CONTENT_EXCRECATOR to CREATE_THE_CONTENT and based on some configurable metric (post score, ad revenue etc.) the investment will accrue dividends, which the subscriber can cash out to a charitable organization. However, this can only be done once per publication per subscriber, meaning the subscriber should wait for the investment to accumulate before cashing in. A global high score will show the subscribers who have cashed in the largest amount in donations and their voting power will be increased in proportion to their score.
I want 15% equity and a public live stream session of the AI box game with Yud where I roleplay as the shittalking French knight from Monty Python and the Holy Grail.
The winning votes will become investments into the post, binding the CONTENT_EXCRECATOR to CREATE_THE_CONTENT and based on some configurable metric (post score, ad revenue etc.) the investment will accrue dividends
I’m in, but only if this part is handled by fractionalizing an NFT linking to the original post on your custom blockchain
@dgerard I’m probably missing something but what is it about these folk and Adderall? They can’t all have self-diagnosed ADHD.. (having an actual psychiatric diagnosis thereof means that I’m just a mean-spirited gatekeeper who thinks people shouldn’t just decide for themselves that they have a serious mental condition and start popping random pills)
@froztbyte Oh, I missed that. So, boring people thinking they can make themselves less boring through pharmaceutical means. 15 years ago it was smart drugs (which weren’t, but that didn’t stop the Bay Area jumping onto that bandwagon with both feet).
At least the people on Shark Tank sometimes bring in cool or entertaining prototypes. Your version would be just slide decks of fintech, vaporware and things that already exist but with a subscription model slapped on.
Ok, read their actual pitch. Lmao they think that a one time introduction of a GMO bacteria strain is going to ‘just work’ because they’ve also GMO’d it to outcompete other bacteria?
There’s a reason we aren’t running our cars on yeast-produced gasoline. No matter how awesome your tuned microbe is, it’s still subject to mutation and natural selection. If your beneficial changes aren’t actually helping it survive, they will not be conserved. And those ‘competitive’ changes you jacked it up with to make sure it dominates the environment? Well, that might end up horizontally transferred into something you don’t like.
About the right amount of ‘we humans are smarter than dumb biology’ metal-fetishism I’d expect from the folks concerned.
Buried in the google drive is a note that this does not remove the need for brushing teeth, but it just notes that not doing that will give you bad breath.
In fact I believe that this is the true cause of this not being a product - people will still need to brush their teeth for other reasons than preventing cavities. If brushing teeth correctly currently lessens the risk of both caries and periodontal disease, having a shot that removes the risk of caries could conceivably mean less conscientious tooth care, which increases the risk of gum problems.
A variant of this organism was first created in 1985, and volunteers deliberately inoculated themselves with the modified strain. This has, to our knowledge, caused no ill effects since.
probably worth someone digging into that to see what else may surround the person
from the “Safety Review and FAQ” document:
Will this spread to everyone I kiss? It’s very unlikely in non-immunocompromised adults. However, if you’re concerned, you should avoid kissing anyone taking oral antibiotics, or children.
“sure let’s just casually become a walking science experiment and then thinking to first ask whether the other person is taking oral antibiotics. oh and children, because mouth-kissing children is perfectly normal to me, the author of this document”
this was from just like 2min of glancing at this mess so far and fucking what
do tell? I’m not aware of this. I’ve mostly managed to avoid having detailed contact with these weirdos, and only in the last few years happened to encounter … their profiles and such. to my knowledge i’ve not yet managed to meet any of the mainliners of this shit in ZA
there’s a poetic irony in target fixating so hard on avoiding one set of weird nutbaggery to then end up as one of the central figures in another bit of nutbaggery…
In before NY times article prints her real name complete with hissie fit followed by transition to Substack and total abandonment of mask of deniability.
Furthermore, we don’t have to worry about regulatory slapdown if we sell it as a medical tourism product in, say, Próspera. We could brand this as a secret medical treatment for the super-elite, like Peter Thiel’s StemcenterX or Minicircle’s regenerative medicine hub, and charge $20,000 a dose.
Synthetic biology as a field is in its infancy. It’s coming along fast and the possibilities are absurdly endless, but it’s hard to overstate how complex of a problem this really is.
The idea that it’ll magically outcompete the rest of your extremely diverse, hyper complex, and largely beneficial mouth biome alone with just one treatment and no maintenance immediately shows it as a scam. We aren’t there yet.
There’s sneer in the pitchdeck about the FDA requiring 300 people healthy people with fully removable teeth isolated from others to trial this, as if it was the dumbest thing ever, instead of a reasonable precaution to introducing an unknown strain of bacteria into everyone’s mouths.
Think the issue here is more that it is run by Rationalists, and they ask 20k for it. (and all the other biotech things they want to do bypassing the FDA, like isn’t that also a NRx thing, he asked rhetorically).
Yeah interesting how there seems to be no big conflict between Scotts ‘I have some beige thoughts about the FDA, it is not bad, buttttttt’ with Yuds ‘BOMBclapALLclapDATACENTERSclap!’
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