I use Brave Browser (with Ublock Origin and AdBlock) and rarely have any issues. I do have Freetube downloaded, installed and ready to go for when they escalate their game (and they will). For certain other applications, a youtube downloader can be quite handy.
Ads truly are the most annoying, counterproductive and least creative way of putting yourself out there. Even worse, they can never seem to match an ad with the content it gets forced upon, and this serves only to train people to associate their brand with uselessness and irrelevance. Even if you have a product that is good, you’ve just presented yourself as an obstructing pair of clown shoes and that becomes your first and long-lasting impression. When the time comes that they may need it, most people will not remember your product from that ad, only that your brand is a pair of clown shoes.
The simple truth is, if you have a good product, you do not need advertising. You only need advertising if you have a bad product and you are worried that negative word of mouth will spread faster than you can dupe your share of people into buying it.
Edit: Replaced a word that may be taken as a slur.