I will echo this. I’m pretty new to homelabbing (I got a Synology NAS a year ago but have just gotten more serious about is and built a new machine last week that I have installed Proxmox and TrueNAS Core on). I haven’t set up remote access yet on the new machine, but for my Synology I have a VPS with Nginx (not NPM just vanilla Nginx) pointing to a VM on the Synology that also has Nginx, with a Wireguard tunnel between them. The VPS uses Nginx to forward ports 80/443 to the local VM (if the headers have appropriate URLs), then the local VM uses Nginx to forward the requests to the locally hosted services.
I’m thinking about dabbling with Traefik to set things up with my new machine, but the VPS+VM (or a container) with proxy capabilities is the way to go. And, of course, have your domain point to the VPS.