First off, a massive portion of Season 3 of Picard revolves around the fact that Picard is a cyborg. So I’m not entirely sure where that “before everybody just agreed not to talk about it” bit comes from. There’s even a reference to him having a synthetic body in Discovery Season 4.
Second, I’ve asked that question of everyone who says that the treknobabble in ‘NuTrek’ doesn’t make sense. No one has ever been able to give me any answer on that at all. A considerable portion of complaints about Discovery, as an example, are wildly unfounded. The ‘it breaks lore/retcons’ complaint is another. There is nothing that I can find that outright breaks lore. Either it’s a misunderstanding, due to it being a visual reboot, or was set up previously by Enterprise.