Adblock DNS, Pi-Hole, hBlock - these three do essentially same thing but at different layers - blocking DNS requests based on blacklists. I’m not familiar with hBlock, but I assume blacklists on each of these 3 are very similar. Using all three doesn’t slow down your internet connection much, unless your pihole server is underpowered. You can drop pi-hole from the mix if you are not using it’s other features (statistics, local DNS, etc). hBlock looks nice, and should add zero latency, but works only for local machine. So you still need network-wide blocker. Make sure you set your DNS on router, so all devices would get protection.
uBlock Origin is smarter than simple DNS blocking, but protects only your browser sessions.