As far as I know Rockstar’s luncher just works fine in Proton, no issues there.
DRM is not a problem anymore unless you pirate (anti-DRM modifications can break in Wine), but it is anti-cheats systems. Some games like Call of Duty Warzone, FIFa 23 and Destiny 2 don’t work because of it. (The last two only because they are programmed to not work on Linux voluntarely, Destiny 2 will ban every Steam account that connect via Proton)
Most devices work out of the box now, tinkering has reduced by a lot especially with easier distros.