dxvk is available through the distro, if you’re on an ubuntu or debian-based distro just run sudo apt install dxvk. vulkan should come pre-installed on any modern distro.
i’d highly recommend using some kind of manager, if you don’t want lutris than use playonlinux which is more minimal. this keeps things organized and lets you use different wine versions and tweaks for each game. for example, some newer games need proton-experimental or an otherwise very recent version to run, but you may not want to replace your system wine with this.