Perhaps this conversation would be more constructive if you told us some of the games you do like, instead of the ones you don’t.
Because I’ll tell you right now, unless you prefer interactive novels which are only arguably games, every game is based on repetitive gameplay.
Specifically, building repetitive gameplay on top of repetitive gameplay is what makes games, games.
Like with chess. You have a repetitive “chess game” loop which has many “your turn” loops inside.
What I’m asking is how you sort it out
To address this specifically, this is what the community of the game is about. It’s why wikis are created and maintained. And so the answer would change based on which game you’re talking about and your goals in that game
For borderlands specifically, a few quick heuristics you can use is to ignore all weapons of not legendary color while in lower level areas, or to stop picking up lower tier items when you don’t need the cash, or to skip everything that isn’t a shotgun because that’s the only piece you need to update