I'm currently getting a lot of mileage out of this in my #Scion campaign. One of the player characters is unknowingly a heir to one of the dynasties of Ultraterrestrial Venice - a dynasty that is currently in exile, and their struggle to return to power is going to be a major campaign arc.
He grew up as an adopted child of an Italian-German family and has started working as a lawyer. But now he is getting glimpses of these deeper background secrets, and he is trying to figure out what it all means.