You should delete your Cyberpunk 2077 mods ahead of update 2.0, and you may need to do a clean reinstall of the game

I figured I was going to have to uninstall my Cyberpunk 2077 mods before checking out Phantom Liberty and update 2.0⁠. Most of the mods I went for on my last playthrough were difficulty and loot adjustments that'd clash with 2.0's big changes, and for the rest, mod authors would likely need to update their files to play nice with the patch. What I wasn't expecting was needing to do a clean reinstall⁠—complete with deleting some leftover files⁠—to clear up a persistent crash on startup.

I'm not sure exactly what borked my game, but big, foundational mod projects like Cyber Engine Tweaks need to be updated with each major patch in turn, and some users in the past have reported similar crash on startup issues to what I experienced. Mod author yamashi has noted on the mod's page that they will be working on a patch 2.0 version of Cyber Engine Tweaks in the coming days.

In the meantime, if you're a returning player, you may want to preemptively pull the nuclear option and do a clean install of Cyberpunk 2077 following CD Projekt's own instructions. The developer recommends:

• First, backup your save files in user/Saved Games/CD Projekt Red/Cyberpunk 2077
• Disable Steam or GOG's cloud save feature for the game (I forgot to do this but still cleared up my issue)
• Uninstall Cyberpunk and delete the following folders:
• The Cyberpunk 2077 folder in your Steam or GOG directory (ex: Seam/steamapps/common/Cyberpunk 2077)
• user/Saved Games/CD Projekt Red/Cyberpunk 2077
• user/AppData/Local/REDEngine
• user/AppData/Local/CD Projekt Red
• Restart your PC, reinstall the game, restore your saves, then reactivate cloud saves if you disabled them.